Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427499 | 0.84 | HPGD (0.46) | KDM4EALDH1A1CYP3A4TSHRATM | |
| SCHEMBL21469067 | 0.81 | ATM (0.68) | ALDH1A1CYP3A4TSHRATMMEN1 | |
| SCHEMBL8530402 | 0.81 | ATM (0.68) | ALDH1A1CYP3A4TSHRATMMEN1 | |
| SCHEMBL30460502 | 0.81 | ATM (0.68) | ALDH1A1CYP3A4TSHRATMMEN1 | |
| SCHEMBL28381567 | 0.78 | ATM (0.60) | CYP3A4TSHRATMMEN1KMT2A | |
| SCHEMBL9371027 | 0.77 | MEN1 (0.58) | KDM4EALDH1A1ATMMEN1KMT2A | |
| SCHEMBL20494542 | 0.77 | TOP2A (0.42) | KDM4EALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL12986619 | 0.76 | MEN1 (0.53) | KDM4EALDH1A1CYP3A4TSHRMEN1 | |
| SCHEMBL18210961 | 0.76 | MEN1 (0.57) | KDM4EALDH1A1CYP3A4TSHRMEN1 | |
| SCHEMBL18356975 | 0.76 | MEN1 (0.57) | KDM4EALDH1A1CYP3A4TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109023-A1 | Isoquinolinesulfonamide derivatives and process for the preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-05-23 | — | — | EP | disclosed |