Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438465 | 1.00 | LMNA (0.64) | LMNACYP2C9PIK3CDOPRL1CHRM2 | |
| SCHEMBL6745315 | 0.83 | — | — | |
| SCHEMBL23315663 | 0.83 | — | — | |
| SCHEMBL2736039 | 0.83 | — | — | |
| SCHEMBL18069713 | 0.83 | — | — | |
| Pseudotropine SCHEMBL745726 | 0.78 | LMNA (1.00) | LMNACYP2C9OPRL1CHRM2CHRM1 | |
| Pseudotropine SCHEMBL21563309 | 0.78 | LMNA (1.00) | LMNACYP2C9OPRL1CHRM2CHRM1 | |
| Pseudotropine SCHEMBL64824 | 0.78 | LMNA (1.00) | LMNACYP2C9OPRL1CHRM2CHRM1 | |
| Pseudotropine SCHEMBL6944859 | 0.78 | LMNA (1.00) | LMNACYP2C9OPRL1CHRM2CHRM1 | |
| Pseudotropine SCHEMBL2442824 | 0.78 | LMNA (1.00) | LMNACYP2C9OPRL1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256656-A | Antiserotonine agent | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| US-5187166-A | Also useful as antipsychotic agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-02-16 | — | — | US | disclosed |
| EP-0469449-A1 | Azabicyclo derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-02-05 | — | — | EP | disclosed |