Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 17/20 | 0.74 |
| ▸ | CTSS | P25774 | 17/20 | 0.74 |
| ▸ | CTSL | P07711 | 16/20 | 0.74 |
| ▸ | CTSK | P43235 | 5/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183543 | 0.85 | CTSB (1.00) | CTSBCTSSCTSLCTSK | |
| SCHEMBL6185943 | 0.83 | CTSB (0.68) | CTSBCTSSCTSLCTSK | |
| SCHEMBL1838437 | 0.80 | CTSB (0.67) | CTSBCTSSCTSLCTSK | |
| SCHEMBL6182540 | 0.80 | CTSB (0.52) | CTSBCTSSCTSLCTSK | |
| SCHEMBL1842461 | 0.80 | CTSB (0.66) | CTSBCTSSCTSLCTSK | |
| SCHEMBL6181475 | 0.79 | CTSB (0.73) | CTSBCTSSCTSLCTSK | |
| SCHEMBL6180697 | 0.78 | CTSL (0.60) | CTSBCTSSCTSLCTSK | |
| SCHEMBL13798777 | 0.77 | CTSB (0.76) | CTSBCTSSCTSLCTSK | |
| SCHEMBL13798776 | 0.77 | CTSB (0.76) | CTSBCTSSCTSLCTSK | |
| SCHEMBL12661358 | 0.77 | CTSB (0.75) | CTSBCTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068645-A2 | N-CYANOMETHYLCARBOXAMIDES AND THEIR USE AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-09-20 | — | — | WO | claimed |
| WO-2001068645-A2 | N-CYANOMETHYLCARBOXAMIDES AND THEIR USE AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-09-20 | — | — | WO | disclosed |