Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MGAM | O43451 | 2/20 | 0.50 |
| ▸ | SI | P14410 | 2/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808572 | 0.86 | MGAM (0.46) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL2701579 | 0.85 | GAA (0.60) | GAAMGAMSIMGAM2CHRM5 | |
| SCHEMBL9064890 | 0.85 | MGAM (0.46) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL10900176 | 0.85 | GAA (0.44) | GAAMGAMSIMGAM2FAAH | |
| SCHEMBL10901101 | 0.83 | FAAH (0.44) | GAAMGAMSIMGAM2FAAH | |
| SCHEMBL10574141 | 0.83 | FAAH (0.44) | GAAMGAMSIMGAM2FAAH | |
| Water SCHEMBL2703341 | 0.82 | GAA (0.57) | GAAMGAMSIMGAM2CHRM5 | |
| SCHEMBL7817166 | 0.81 | MGAM (0.44) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL16411225 | 0.80 | MGAM (0.55) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL649327 | 0.80 | MGAM (0.55) | GAAMGAMSIMGAM2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103450114-B | The chloro-6-methyl isophthalic acid of 5-, the synthetic method of 2,3-Yang oxazine-4 (3H)-one-2,2-dioxide | SUZHOU HAOBO TECHNOLOGY HOLDINGS CO., LTD. (CN) | 2015-09-02 | — | — | CN | claimed |
| CN-103592402-B | Method for detecting ethyl 2-chloroacetoacetate in ethyl 4-chloroacetoacetate | SUZHOU HOPE TECHNOLOGY CO LTD | 2015-06-10 | — | — | CN | claimed |
| CN-103592402-A | Method for detecting ethyl 2-chloroacetoacetate in ethyl 4-chloroacetoacetate | SUZHOU HOPE TECHNOLOGY CO LTD | 2014-02-19 | — | — | CN | claimed |
| CN-103450114-A | Synthetic method of 5-chloro-6-methyl-1,2,3-oxyoxazine-4(3H)-keto-2,2-dioxide | SUZHOU HOPE TECHNOLOGY CO LTD | 2013-12-18 | — | — | CN | claimed |
| CN-103030605-A | Preparation method and detection method of febuxostat raw material | GUIZHOU XINBANG PHARMACEUTICAL CO LTD | 2013-04-10 | — | — | CN | claimed |
| CN-102936230-A | New preparation method of febuxostat | Ge changle | 2013-02-20 | — | — | CN | claimed |
| EP-4408827-A1 | A NEW INTERMEDIATE FOR PREPARATION OF OXAZOLE COMPOUNDS | DSM IP Assets B.V. (NL) | 2024-08-07 | — | — | EP | disclosed |
| EP-4408828-A1 | A PROCESS FOR PREPARATION OF OXAZOLE COMPOUNDS | DSM IP Assets B.V. (NL) | 2024-08-07 | — | — | EP | disclosed |
| CN-112638898-B | Heteroaryl substituted sulfonamide compounds and their use as sodium channel inhibitors | 泽农医药公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117551026-A | Preparation method and application of nicardipine hydrochloride impurity | 成都地奥九泓制药厂 | 2024-02-13 | — | — | CN | disclosed |
| CN-117209418-A | Preparation and purification method of high-purity nicardipine hydrochloride | 华仁医学研究(安徽)有限公司 | 2023-12-12 | — | — | CN | disclosed |
| EP-4192820-A1 | A PROCESS FOR PREPARATION OF OXAZOLE COMPOUNDS | DSM IP Assets B.V. (NL) | 2023-06-14 | — | — | EP | disclosed |
| WO-2023052103-A1 | A NEW INTERMEDIATE FOR PREPARATION OF OXAZOLE COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2023-04-06 | — | — | WO | disclosed |
| US-4404378-A | HYPOTENSIVE AGENTS; VASODILATION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1983-09-13 | — | — | US | disclosed |
| US-4370334-A | VASODILATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-01-25 | — | — | US | disclosed |
| EP-0063747-A1 | 2-Substituted or unsubstituted aminocarbonyloxyalkyl-1,4-dihydropyridines | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1982-11-03 | — | — | EP | disclosed |
| US-4338322-A | 1,4-Dihydropyridine derivatives, pharmaceutical compositions containing same and methods of effecting vasodilation using same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-07-06 | — | — | US | disclosed |
| US-4284634-A | HYPOTENSIVE VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-08-18 | — | — | US | disclosed |
| US-4145432-A | 6-ACYLORYALKYL-1,4-DIHYDROPYRIDINE DERIVATIVES AND A METHOD OF EFFECTING VASODILATION THEREWITH | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-3985758-A | 1,4-Dihydropyridine derivatives | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1976-10-12 | — | — | US | disclosed |