Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18325768 | 0.87 | SLC22A12 (0.48) | F2RL3ALDH1A1MAPTHPGDSLC22A12 | |
| SCHEMBL7423357 | 0.86 | F2RL3 (0.43) | F2RL3ALDH1A1MAPTHPGDSLC22A12 | |
| SCHEMBL6604398 | 0.86 | F2RL3 (0.43) | F2RL3ALDH1A1MAPTHPGDSLC22A12 | |
| SCHEMBL16345312 | 0.86 | F2RL3 (0.43) | F2RL3ALDH1A1MAPTHPGDSLC22A12 | |
| SCHEMBL16795577 | 0.85 | F2RL3 (0.40) | F2RL3ALDH1A1MAPTHPGDSLC22A12 | |
| SCHEMBL7429570 | 0.83 | F2RL3 (0.44) | F2RL3ALDH1A1MAPTHPGDSLC22A12 | |
| SCHEMBL18317797 | 0.80 | ALDH1A1 (0.40) | F2RL3ALDH1A1MAPTHPGDSLC22A12 | |
| SCHEMBL16345291 | 0.79 | F2RL3 (0.38) | F2RL3ALDH1A1MAPTHPGDSLC22A12 | |
| SCHEMBL16345511 | 0.79 | F2RL3 (0.38) | F2RL3ALDH1A1MAPTHPGDSLC22A12 | |
| SCHEMBL16345751 | 0.78 | F2RL3 (0.46) | F2RL3ALDH1A1MAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054884-A1 | BENZOFURAN-4-CARBOXAMIDES AND THEIR THERAPEUTIC USE | Darwin Discovery Limited (GB) | 2000-11-29 | — | — | EP | disclosed |
| US-6066657-A | Benzofuran-4-carboxamides and their therapeutic use | DARWIN DISCOVERY, LTD. (GB) | 2000-05-23 | — | — | US | disclosed |
| WO-1999040085-A1 | BENZOFURAN-4-CARBOXAMIDES AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LIMITED (GB) | 1999-08-12 | — | — | WO | disclosed |