Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430466 | 0.91 | ADORA3 (0.53) | ADORA3CACNA1CHIF1AMEN1KMT2A | |
| SCHEMBL7426393 | 0.86 | ADORA3 (0.54) | ADORA3CACNA1CHIF1AMEN1KMT2A | |
| SCHEMBL11829575 | 0.86 | ADORA3 (0.69) | ADORA3CACNA1CHIF1AMEN1KMT2A | |
| SCHEMBL11376477 | 0.83 | CACNA1C (0.56) | ADORA3CACNA1CHIF1AMEN1KMT2A | |
| SCHEMBL11690943 | 0.82 | ADORA3 (0.61) | ADORA3CACNA1CHIF1AMEN1KMT2A | |
| SCHEMBL7434261 | 0.82 | CYP2C9 (0.55) | ADORA3CACNA1CHIF1AMEN1KMT2A | |
| SCHEMBL7425673 | 0.81 | ADORA3 (0.68) | ADORA3CACNA1CHIF1AKMT2AMAPT | |
| SCHEMBL7273495 | 0.80 | CYP1A2 (0.65) | ADORA3CACNA1CHIF1AMEN1KMT2A | |
| SCHEMBL7273500 | 0.80 | CYP1A2 (0.65) | ADORA3CACNA1CHIF1AMEN1KMT2A | |
| SCHEMBL7434487 | 0.80 | CYP1A2 (0.57) | ADORA3CACNA1CHIF1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125803-A2 | Pharmaceutically active dihydropyridines | FISONS plc (GB) | 1984-11-21 | — | — | EP | claimed |