Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 0.67 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.55 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350747 | 0.86 | HTR1A (0.88) | HTR1A | |
| SCHEMBL7427779 | 0.86 | SLC7A5 (0.61) | HTR1ASLC7A5CACNA2D1 | |
| SCHEMBL7437571 | 0.85 | HTR1A (0.55) | HTR1ACACNA2D1 | |
| SCHEMBL7443700 | 0.85 | HTR1A (0.63) | HTR1A | |
| SCHEMBL10053312 | 0.79 | HTR1A (0.76) | HTR1A | |
| SCHEMBL10052737 | 0.77 | HTR1A (0.80) | HTR1A | |
| SCHEMBL349866 | 0.77 | HTR1A (0.69) | HTR1ASLC7A5 | |
| SCHEMBL7431833 | 0.77 | HTR1A (0.74) | HTR1A | |
| SCHEMBL7435344 | 0.75 | HTR1A (0.55) | HTR1A | |
| SCHEMBL10052723 | 0.74 | HTR1A (1.00) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571685-A1 | Aryloxyheteroarylpropylamines, their preparation and use | NOVO NORDISK A/S (DK) | 1993-12-01 | — | — | EP | disclosed |