Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435077 | 0.87 | LTA4H (0.47) | HTR1AKDM4EALDH1A1LMNAGAA | |
| SCHEMBL7443700 | 0.79 | HTR1A (0.63) | HTR1A | |
| SCHEMBL7428297 | 0.77 | HTR1A (0.53) | HTR1A | |
| SCHEMBL7442963 | 0.76 | HTR1A (0.51) | HTR1AKDM4EALDH1A1 | |
| SCHEMBL10053312 | 0.75 | HTR1A (0.76) | HTR1ASIGMAR1 | |
| SCHEMBL7427735 | 0.75 | HTR1A (0.67) | HTR1A | |
| SCHEMBL10485755 | 0.74 | MAPT (0.56) | SIGMAR1KDM4EALDH1A1LMNAGAA | |
| SCHEMBL10021769 | 0.74 | HTR1A (0.80) | HTR1ASIGMAR1 | |
| SCHEMBL350747 | 0.73 | HTR1A (0.88) | HTR1A | |
| SCHEMBL10052737 | 0.73 | HTR1A (0.80) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571685-A1 | Aryloxyheteroarylpropylamines, their preparation and use | NOVO NORDISK A/S (DK) | 1993-12-01 | — | — | EP | disclosed |