Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.64 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.64 |
| ▸ | PAM | P19021 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433097 | 1.00 | S1PR1 (0.64) | S1PR1S1PR3PAMALDH1A1MAOB | |
| SCHEMBL3273935 | 0.87 | S1PR1 (0.57) | S1PR1S1PR3ALDH1A1MAOB | |
| SCHEMBL4499317 | 0.87 | S1PR1 (0.51) | S1PR1S1PR3PAMALDH1A1MAOB | |
| SCHEMBL6343465 | 0.86 | PAM (0.58) | S1PR1S1PR3PAMALDH1A1MAOB | |
| SCHEMBL6343467 | 0.86 | PAM (0.58) | S1PR1S1PR3PAMALDH1A1MAOB | |
| SCHEMBL11597357 | 0.83 | PRMT1 (0.55) | S1PR1S1PR3PAMALDH1A1MAOB | |
| SCHEMBL11597360 | 0.83 | PRMT1 (0.55) | S1PR1S1PR3PAMALDH1A1MAOB | |
| SCHEMBL6898148 | 0.80 | PRMT1 (0.50) | S1PR1S1PR3PAMALDH1A1MAOB | |
| SCHEMBL6898155 | 0.80 | PRMT1 (0.50) | S1PR1S1PR3PAMALDH1A1MAOB | |
| SCHEMBL2770965 | 0.79 | KDM4E (0.55) | PAMALDH1A1MAOBPRMT1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061631-A1 | MODIFIED PENTAPEPTIDE ANTAGONISTS OF THE ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR | ASTRAZENECA AB (SE) | 2000-10-19 | — | — | WO | disclosed |