Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.57 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427930 | 0.87 | S1PR1 (0.64) | S1PR1S1PR3MAOBALDH1A1 | |
| SCHEMBL7433097 | 0.87 | S1PR1 (0.64) | S1PR1S1PR3MAOBALDH1A1 | |
| SCHEMBL18979186 | 0.78 | AKR1B10 (0.52) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| SCHEMBL9574442 | 0.78 | AKR1B10 (0.52) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| SCHEMBL11023328 | 0.74 | ESR1 (0.40) | S1PR1S1PR3AKR1B10AKR1B1MAOB | |
| SCHEMBL4499317 | 0.74 | S1PR1 (0.51) | S1PR1S1PR3MAOBMMP1MMP2 | |
| SCHEMBL9502575 | 0.73 | PAM (0.70) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| SCHEMBL1616362 | 0.73 | PAM (0.70) | AKR1B10AKR1B1MAOBPTGS2GLO1 | |
| Hydrochloric Acid SCHEMBL947492 | 0.73 | S1PR1 (0.67) | S1PR1S1PR3 | |
| SCHEMBL31627390 | 0.73 | PRMT1 (0.64) | S1PR1S1PR3ESR1ESR2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399213-B2 | Method for monitoring intracellular tyrosine phosphatase activity | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-03-19 | — | — | US | claimed |
| WO-2010039899-A2 | METHOD FOR MONITORING INTRACELLULAR TYROSINE PHOSPHATASE ACTIVITY | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2010-04-08 | — | — | WO | claimed |
| US-20100086957-A1 | METHOD FOR MONITORING INTRACELLULAR TYROSINE PHOSPHATASE ACTIVITY | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2010-04-08 | — | — | US | claimed |
| US-8399213-B2 | Method for monitoring intracellular tyrosine phosphatase activity | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-03-19 | — | — | US | disclosed |
| WO-2010039899-A2 | METHOD FOR MONITORING INTRACELLULAR TYROSINE PHOSPHATASE ACTIVITY | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2010-04-08 | — | — | WO | disclosed |
| US-20100086957-A1 | METHOD FOR MONITORING INTRACELLULAR TYROSINE PHOSPHATASE ACTIVITY | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100086957-A1 | METHOD FOR MONITORING INTRACELLULAR TYROSINE PHOSPHATASE ACTIVITY | PTPRCAP, PTPRC, PTPA | S1PR1 1890/4885S1PR3 1850/4885AKR1B10 4164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.