Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575108 | 0.89 | REN (0.45) | RENCTSSCTSLCTSB | |
| SCHEMBL9575055 | 0.88 | REN (0.45) | RENCTSSCTSL | |
| SCHEMBL9574994 | 0.88 | REN (0.47) | REN | |
| SCHEMBL7427996 | 0.87 | PLK1 (0.36) | RENCTSSCTSLCTSB | |
| SCHEMBL9575021 | 0.84 | CTSS (0.49) | RENCTSSCTSLCTSB | |
| SCHEMBL9575107 | 0.84 | REN (0.38) | RENCTSSCTSLCTSB | |
| SCHEMBL7382471 | 0.83 | CTSS (0.39) | RENCTSSCTSLCTSB | |
| SCHEMBL9574993 | 0.83 | REN (0.39) | REN | |
| SCHEMBL9575025 | 0.81 | REN (0.46) | REN | |
| SCHEMBL9575060 | 0.80 | CTSS (0.33) | RENCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217958-A | Hypotensive agents | E. R. SQUIBB & SONS, INC. (US) | 1993-06-08 | — | — | US | disclosed |
| WO-1989007940-A1 | 1,2-HYDROXY PHOSPHONATES AND DERIVATIVES THEREOF | E.R. SQUIBB & SONS, INC. (US) | 1989-09-08 | — | — | WO | disclosed |
| EP-0331105-A2 | 1,2-Hydroxy phosphonates and derivatives thereof | E.R. Squibb & Sons, Inc. (US) | 1989-09-06 | — | — | EP | disclosed |