SCHEMBL742810

SCHEMBL742810

CC(=O)Oc1cccc(C)c1C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.62
POLB P06746 1/20 0.57
PTPN1 P18031 2/20 0.56
MAPT P10636 3/20 0.51
KDM4E B2RXH2 4/20 0.50
HSD17B10 Q99714 4/20 0.50
ALDH1A1 P00352 3/20 0.50
HPGD P15428 2/20 0.50
MAPK1 P28482 1/20 0.50
ESR1 P03372 1/20 0.50
ITGB3 P05106 1/20 0.50
ITGA2B P08514 1/20 0.50
HMGB1 P09429 1/20 0.50
TSHR P16473 1/20 0.50
GGT1 P19440 1/20 0.50
PTGS1 P23219 1/20 0.50
PTGS2 P35354 1/20 0.50
BLM P54132 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31229899 1.00 ACHE (0.62) ACHEPOLBPTPN1MAPTKDM4E
SCHEMBL11585900 0.98 ACHE (0.61) ACHEPOLBPTPN1MAPTKDM4E
SCHEMBL544041 0.89 ACHE (0.69) ACHEPOLBPTPN1MAPTKDM4E
SCHEMBL6537087 0.85 POLB (0.59) ACHEPOLBPTPN1MAPTALDH1A1
SCHEMBL1803105 0.85 POLB (0.59) ACHEPOLBPTPN1MAPTALDH1A1
SCHEMBL29525400 0.85 POLB (0.59) ACHEPOLBPTPN1MAPTALDH1A1
SCHEMBL5338818 0.83 ACHE (0.54) ACHEPOLBPTPN1KDM4EHSD17B10
SCHEMBL6404160 0.83 POLB (0.57) ACHEPOLBPTPN1MAPTALDH1A1
SCHEMBL1837507 0.83 POLB (0.57) ACHEPOLBMAPTKDM4EHSD17B10
SCHEMBL30179347 0.83 PTGS2 (0.59) ACHEPTPN1KDM4EHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260072035-A1 ENHANCED SPECIFICITY MASS TAG DNA ADDUCTOMICS UNIV NORTHEASTERN (US) 2026-03-12 US claimed
EP-4511513-A1 ENHANCED SPECIFICITY MASS TAG DNA ADDUCTOMICS Northeastern University (US) 2025-02-26 EP claimed
US-20240057595-A1 INSECT REPELLENT COMPOSITIONS SYMBIOTIC CAPITAL AGENCY LLC, AS ADMINISTRATIVE AND COLLATERAL AGENT 2024-02-22 US claimed
WO-2023239572-A1 ENHANCED SPECIFICITY MASS TAG DNA ADDUCTOMICS NORTHEASTERN UNIVERSITY (US) 2023-12-14 WO claimed
WO-2022147076-A1 INSECT REPELLENT COMPOSITIONS MANUS BIO INC. (US) 2022-07-07 WO claimed
WO-2011060028-A1 LIQUID LAUNDRY DETERGENT COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2011-05-19 WO claimed
WO-2011059714-A1 SOLID LAUNDRY DETERGENT COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2011-05-19 WO claimed
EP-2322593-A1 Liquid laundry detergent composition The Procter & Gamble Company (US) 2011-05-18 EP claimed
EP-2322595-A1 Solid laundry detergent composition The Procter & Gamble Company (US) 2011-05-18 EP claimed
US-20110112005-A1 Laundry Detergent Composition PROCTER & GAMBLE COMPANY, THE 2011-05-12 US claimed
US-7648953-B2 Eco-friendly laundry detergent compositions comprising natural essence THE DIAL CORPORATION (US) 2010-01-19 US claimed
US-20090281010-A1 Eco-friendly laundry detergent compositions comprising natural essence HENKEL AG & CO. KGAA (DE) 2009-11-12 US claimed
US-4212989-A ARYL ESTER SOLVENTS USED IN CATALYTIC CARBONYLATION FO ALCOHOLS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1980-07-15 US claimed
US-12162863-B2 Modulators of stimulator of interferon genes (STING) Ryvu Therapeutics S.A. (PL) 2024-12-10 US disclosed
US-20240075043-A1 IMMEDIATE AND CONTROLLED RELEASE APPETITE SUPPRESSANT COMPOSITIONS FOR WEIGHT LOSS Red Mountain Med Spa, LLC (US) 2024-03-07 US disclosed
US-20240057595-A1 INSECT REPELLENT COMPOSITIONS SYMBIOTIC CAPITAL AGENCY LLC, AS ADMINISTRATIVE AND COLLATERAL AGENT 2024-02-22 US disclosed
EP-0019294-A1 N,N'diacyl-ethane-1,2 diamines, their preparation and their pesticidal formulations THE WELLCOME FOUNDATION LIMITED (GB) 1980-11-26 EP disclosed
US-4234733-A PHENOL, ALIPHATIC ESTER OR ETHER, CARBON MONOXIDE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1980-11-18 US disclosed
US-4212989-A ARYL ESTER SOLVENTS USED IN CATALYTIC CARBONYLATION FO ALCOHOLS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1980-07-15 US disclosed
US-4056572-A Method for the manufacture of phenols BASHKIROV ANDREI NIKOLAEVICH 1977-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12162863-B2 Modulators of stimulator of interferon genes (STING) STING1, IRF3, CGAS ACHE 4250/4885POLB 292/4885PTPN1 2115/4885
US-20260072035-A1 ENHANCED SPECIFICITY MASS TAG DNA ADDUCTOMICS DNMT3A, APEX1, CHAMP1 ACHE 1336/4885POLB 228/4885PTPN1 1997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.