Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10423138 | 0.87 | HPGD (0.64) | HPGDKMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL4634361 | 0.83 | RECQL (0.69) | HPGDKMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL1053081 | 0.82 | MTNR1A (0.69) | HPGDMTNR1AMTNR1BRECQLSMN1; SMN2 | |
| SCHEMBL17620424 | 0.81 | HPGD (0.78) | HPGDKMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL1326062 | 0.79 | PARP10 (0.61) | HPGDRECQLTAAR1SMN1; SMN2RAB9A | |
| SCHEMBL1328579 | 0.79 | PARP10 (0.61) | MTNR1AMTNR1BRECQLTAAR1RAB9A | |
| SCHEMBL11253171 | 0.79 | NPC1 (0.60) | HPGDKMT2AMEN1RECQLSMN1; SMN2 | |
| SCHEMBL17621160 | 0.79 | HPGD (0.94) | HPGDKMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL19185423 | 0.79 | HPGD (0.62) | HPGDKMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL4576541 | 0.79 | MTNR1A (0.65) | HPGDKMT2AMEN1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082127-A4 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2002-10-09 | — | — | EP | claimed |
| EP-1082127-A1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME | WARNER-LAMBERT COMPANY (US) | 2001-03-14 | — | — | EP | claimed |
| WO-1999056765-A1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME | WARNER-LAMBERT COMPANY (US) | 1999-11-11 | — | — | WO | claimed |