Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | MRE11 | P49959 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.47 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424422 | 1.00 | MEN1 (0.53) | MEN1KMT2ASTAT3MRE11CAPN1 | |
| SCHEMBL7424619 | 0.83 | MRE11 (0.46) | MEN1KMT2ASTAT3MRE11CAPN1 | |
| SCHEMBL21241786 | 0.81 | HDAC6 (0.61) | MEN1KMT2ASTAT3MRE11CAPN1 | |
| SCHEMBL22971723 | 0.81 | HDAC6 (0.61) | MEN1KMT2ASTAT3MRE11CAPN1 | |
| SCHEMBL21241768 | 0.80 | SCD (0.60) | MEN1KMT2ASTAT3CAPN1MAPT | |
| SCHEMBL21241787 | 0.80 | SCD (0.60) | MEN1KMT2ASTAT3CAPN1MAPT | |
| SCHEMBL5869395 | 0.79 | MEN1 (0.60) | MEN1KMT2ASTAT3MAPTELOVL1 | |
| SCHEMBL5869382 | 0.79 | MEN1 (0.60) | MEN1KMT2ASTAT3MAPTELOVL1 | |
| SCHEMBL5869368 | 0.79 | MEN1 (0.60) | MEN1KMT2ASTAT3MAPTELOVL1 | |
| SCHEMBL7426239 | 0.79 | MEN1 (0.43) | MEN1KMT2ASTAT3CAPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |