Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRE11 | P49959 | 4/20 | 0.46 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428381 | 0.83 | MEN1 (0.53) | MRE11MAPTELOVL1NPC1RAB9A | |
| SCHEMBL7424422 | 0.83 | MEN1 (0.53) | MRE11MAPTELOVL1NPC1RAB9A | |
| SCHEMBL22491245 | 0.76 | MAPT (0.48) | MAPTNPC1RAB9ACASP3SENP7 | |
| SCHEMBL7424611 | 0.75 | ELOVL1 (0.46) | MAPTELOVL1NPC1RAB9ACASP3 | |
| SCHEMBL7422773 | 0.75 | RAB9A (0.46) | MAPTNPC1RAB9ACASP3SENP7 | |
| SCHEMBL3335375 | 0.74 | MRE11 (0.67) | MRE11GPR142MAPTELOVL1NPC1 | |
| SCHEMBL3331466 | 0.72 | PKM (0.65) | MRE11GPR142MAPTELOVL1NPC1 | |
| SCHEMBL29276746 | 0.71 | LMNA (0.58) | MRE11GPR142MAPTELOVL1RAB9A | |
| SCHEMBL5869395 | 0.71 | MEN1 (0.60) | MAPTELOVL1NPC1RAB9ACASP3 | |
| SCHEMBL5869382 | 0.71 | MEN1 (0.60) | MAPTELOVL1NPC1RAB9ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |