Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL830095 | 0.77 | CA1 (0.50) | CA1CA2CA12CA7CA4 | |
| SCHEMBL7418813 | 0.76 | KDM4E (0.42) | KMT2AGAAPOLBCTDSP1 | |
| SCHEMBL23112824 | 0.72 | CA1 (0.61) | CA1CA2CA12CA7CA4 | |
| SCHEMBL27911568 | 0.70 | CNR1 (0.60) | CA1CA2CA12CA7CA4 | |
| SCHEMBL4598881 | 0.69 | HPGD (0.64) | CA1CA2CA12CA7CA4 | |
| SCHEMBL7428073 | 0.67 | TP53 (0.41) | FPR2FPR3SMN1; SMN2TP53CTDSP1 | |
| SCHEMBL1665183 | 0.66 | OGG1 (0.59) | CA1CA2CA12CA9MEN1 | |
| SCHEMBL23113031 | 0.65 | CA1 (0.53) | CA1CA2CA12CA7CA4 | |
| SCHEMBL4766928 | 0.65 | CA1 (0.52) | CA1CA2CA12CA7CA4 | |
| SCHEMBL3041532 | 0.65 | AGER (0.48) | MAPTMEN1KMT2AGAAFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002070469-A2 | SELECTIVE PDE3B INHIBITORS AND USE OF THE SAME IN THERAPY | ICOS CORPORATION (US) | 2002-09-12 | — | — | WO | disclosed |