Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Cyclohexane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopropane SCHEMBL28632838 | 0.84 | — | — | |
| Cyclohexane SCHEMBL28653718 | 0.80 | — | — | |
| Cyclohexane SCHEMBL22283847 | 0.80 | — | — | |
| Bromide SCHEMBL11044355 | 0.80 | — | — | |
| Cyclopropane SCHEMBL18956919 | 0.80 | — | — | |
| Cyclohexane SCHEMBL3859858 | 0.80 | — | — | |
| Cyclopentane SCHEMBL9234236 | 0.80 | — | — | |
| Cyclohexane SCHEMBL23142614 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL286862 | 0.78 | — | — | |
| SCHEMBL173379 | 0.78 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113637041-A | Preparation method of ribonucleoside | 上海科胜药物研发有限公司 | 2021-11-12 | — | — | CN | claimed |
| CN-113549120-B | Method for preparing ribonucleoside | 吉利德科学公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-118754171-B | High-dispersion nano high-purity magnesia powder and preparation method thereof | 山东工业陶瓷研究设计院有限公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-119039340-A | Preparation method of diethylamino trialkoxysilane | 湖北华邦化学有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-118812607-A | Method for preparing ribonucleoside | 吉利德科学公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118561303-B | Low-cost high-purity high-densification spherical magnesia powder and preparation method thereof | 山东工业陶瓷研究设计院有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118561305-B | High-heat-conductivity high-purity spherical magnesium oxide precursor and preparation method thereof | 山东工业陶瓷研究设计院有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118754171-A | High-dispersion nano high-purity magnesia powder and preparation method thereof | 山东工业陶瓷研究设计院有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-118561303-A | Low-cost high-purity high-densification spherical magnesia powder and preparation method thereof | 山东工业陶瓷研究设计院有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-118561305-A | High-heat-conductivity high-purity spherical magnesium oxide precursor and preparation method thereof | 山东工业陶瓷研究设计院有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-111018923-B | Carbohydrate monophosphines, method for the production and use thereof | 东莞市均成高新材料有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-113637041-B | Preparation method of ribonucleoside | 上海科胜药物研发有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-113637041-A | Preparation method of ribonucleoside | 上海科胜药物研发有限公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-113549120-A | Process for preparing ribonucleosides | 吉利德科学公司 | 2021-10-26 | — | — | CN | disclosed |
| US-20160102058-A1 | FLUORO-PERHEXILINE COMPOUNDS AND THEIR THERAPEUTIC USE | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2016-04-14 | — | — | US | disclosed |
| EP-2997012-A1 | FLUORO-PERHEXILINE COMPOUNDS AND THEIR THERAPEUTIC USE | The University Court of The University of Aberdeen (GB) | 2016-03-23 | — | — | EP | disclosed |
| WO-2014184561-A1 | FLUORO-PERHEXILINE COMPOUNDS AND THEIR THERAPEUTIC USE | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2014-11-20 | — | — | WO | disclosed |
| WO-2002070469-A2 | SELECTIVE PDE3B INHIBITORS AND USE OF THE SAME IN THERAPY | ICOS CORPORATION (US) | 2002-09-12 | — | — | WO | disclosed |