Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | PRKCA | P17252 | 2/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431215 | 0.89 | PRKCA (0.60) | ADRB2ADRB1ADRB3PRKCAPRKCD | |
| SCHEMBL7428462 | 0.84 | SYK (0.50) | PRKCAPRKCDSYKLTA4HNPC1 | |
| SCHEMBL1553476 | 0.84 | SYK (0.54) | ADRB2ADRB1ADRB3PRKCAPRKCD | |
| SCHEMBL30771411 | 0.83 | SYK (0.53) | ADRB2ADRB1ADRB3PRKCAPRKCD | |
| SCHEMBL9533724 | 0.81 | SYK (0.51) | ADRB2ADRB1ADRB3PRKCAPRKCD | |
| SCHEMBL31724393 | 0.81 | SYK (0.54) | ADRB2ADRB1ADRB3PRKCAPRKCD | |
| SCHEMBL20425275 | 0.79 | SYK (0.53) | ADRB2ADRB1ADRB3SYKLTA4H | |
| SCHEMBL17602183 | 0.79 | MAPT (0.54) | SYKLTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5667786 | 0.78 | SYK (0.55) | SYKMAPT | |
| SCHEMBL7428446 | 0.78 | ATM (0.61) | ADRB2ADRB1ADRB3SYKLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000006559-A1 | REDUCED DIPEPTIDE ANALOGUES AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |