Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27629487 | 0.87 | PARP1 (0.43) | BCL2BCL2L1MEN1KMT2ACYP3A4 | |
| SCHEMBL5775272 | 0.86 | PARP1 (0.44) | BCL2BCL2L1TSHRMEN1KMT2A | |
| SCHEMBL22290169 | 0.83 | MAPT (0.40) | MEN1KMT2AHCAR2PARP1 | |
| SCHEMBL29339712 | 0.82 | TP53 (0.40) | BCL2BCL2L1TSHRMEN1KMT2A | |
| SCHEMBL7421266 | 0.82 | ALDH1A1 (0.40) | BCL2BCL2L1TSHRMEN1KMT2A | |
| SCHEMBL4857853 | 0.81 | BCL2 (0.48) | BCL2BCL2L1ALOX5MEN1KMT2A | |
| SCHEMBL7458172 | 0.78 | PARP1 (0.45) | BCL2BCL2L1ALOX5MEN1KMT2A | |
| SCHEMBL22083543 | 0.74 | DAO (0.43) | BCL2BCL2L1TSHRMEN1KMT2A | |
| SCHEMBL16148679 | 0.74 | TYMP (0.42) | BCL2BCL2L1ALOX5MEN1KMT2A | |
| SCHEMBL3501919 | 0.74 | MPO (0.44) | MEN1KMT2ACYP3A4METCALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |