Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428618 | 1.00 | GLO1 (0.78) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL8018753 | 0.93 | GLO1 (0.90) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL11681247 | 0.90 | GLO1 (0.82) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL7475824 | 0.88 | GLO1 (0.78) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL7475820 | 0.88 | GLO1 (0.78) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL10757963 | 0.88 | GLO1 (0.78) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL6137191 | 0.88 | GLO1 (1.00) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL11776075 | 0.88 | GLO1 (0.82) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL7312484 | 0.88 | GLO1 (1.00) | GLO1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL29419555 | 0.88 | GLO1 (1.00) | GLO1KMT2ALMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4607041-A | CARDIOTONIC AGENTS | FISONS PLC (GB) | 1986-08-19 | — | — | US | disclosed |
| EP-0125803-A2 | Pharmaceutically active dihydropyridines | FISONS plc (GB) | 1984-11-21 | — | — | EP | disclosed |