Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | PREP | P48147 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1070012 | 0.84 | CA12 (0.48) | CA12CA1CA9PREPALDH1A1 | |
| SCHEMBL14240879 | 0.84 | CA12 (0.48) | CA12CA1CA9PREPALDH1A1 | |
| SCHEMBL22078670 | 0.83 | CA12 (0.47) | CA12CA1CA9PREPALDH1A1 | |
| SCHEMBL19810818 | 0.83 | ALDH1A1 (0.49) | CA12CA1CA9PREPALDH1A1 | |
| SCHEMBL17494765 | 0.81 | CA12 (0.46) | CA12CA1CA9PREPALDH1A1 | |
| SCHEMBL7618394 | 0.81 | TYR (0.58) | CA12CA1CA9PREPALDH1A1 | |
| SCHEMBL2511093 | 0.81 | CA12 (0.46) | CA12CA1CA9PREPALDH1A1 | |
| SCHEMBL6841139 | 0.81 | CA12 (0.48) | CA12CA1CA9PREPALDH1A1 | |
| SCHEMBL2199657 | 0.81 | CA12 (0.48) | CA12CA1CA9PREPALDH1A1 | |
| SCHEMBL5383976 | 0.80 | ALDH1A1 (0.63) | CA12CA1CA9ALDH1A1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107954-A1 | 2-OXO-$i(2H)-QUINOLINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012479-A1 | 2-OXO-2H-QUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-03-09 | — | — | WO | disclosed |