Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1835409 | 0.86 | KCNA3 (0.54) | KCNA3L3MBTL1LTA4HALDH1A1RECQL | |
| SCHEMBL11017099 | 0.82 | GAA (0.47) | HDAC1L3MBTL1 | |
| SCHEMBL19513276 | 0.82 | HTT (0.69) | L3MBTL1ALDH1A1 | |
| SCHEMBL10361085 | 0.81 | HDAC1 (0.65) | KCNA3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL7069051 | 0.81 | LTA4H (0.68) | KCNA3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL15292057 | 0.81 | HDAC1 (0.56) | KCNA3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL10904079 | 0.79 | KCNA3 (0.94) | KCNA3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL497029 | 0.79 | KCNA3 (0.94) | KCNA3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL2512157 | 0.79 | KCNA3 (0.94) | KCNA3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL9011596 | 0.79 | KCNA3 (0.94) | KCNA3HDAC1HDAC2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046590-A2 | Phen(alk)oxy-substituted oxirane-carboxylic acids, process for their preparation, their use and drugs containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-03-03 | — | — | EP | disclosed |