Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.62 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429684 | 0.89 | F10 (0.59) | F10PLA2G10F2KLK1 | |
| SCHEMBL7425299 | 0.84 | F10 (0.53) | F10PLA2G10KMT2A | |
| SCHEMBL6436996 | 0.78 | F10 (0.71) | F10PLA2G10F2 | |
| SCHEMBL6434131 | 0.77 | F10 (0.59) | F10PLA2G10F2 | |
| Trifluoroacetic Acid SCHEMBL7717317 | 0.77 | F10 (1.00) | F10F2 | |
| SCHEMBL27497122 | 0.76 | CENPE (0.40) | F10 | |
| SCHEMBL6436769 | 0.75 | F10 (0.67) | F10PLA2G10F2 | |
| Trifluoroacetic Acid SCHEMBL7717313 | 0.75 | F10 (0.96) | F10F2 | |
| SCHEMBL27497454 | 0.74 | PLA2G10 (0.74) | F10PLA2G10F2 | |
| SCHEMBL6433559 | 0.73 | F10 (0.81) | F10PLA2G10F2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |