Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.53 |
| ▸ | CCR2 | P41597 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BUB1 | O43683 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429297 | 0.89 | F10 (0.50) | F10CCR2CNR1PLA2G10POLB | |
| SCHEMBL7428962 | 0.84 | F10 (0.62) | F10KMT2APLA2G10 | |
| SCHEMBL6432441 | 0.78 | F10 (0.58) | F10CCR2CNR1 | |
| SCHEMBL6432403 | 0.76 | CCR2 (0.50) | F10CCR2CNR1 | |
| SCHEMBL6432886 | 0.75 | F10 (0.56) | F10CCR2CNR1POLBPPARG | |
| SCHEMBL6433076 | 0.73 | CCR2 (0.77) | F10CCR2PLA2G10 | |
| SCHEMBL6433060 | 0.73 | F10 (0.71) | F10CCR2CNR1PLA2G10PPARG | |
| SCHEMBL7429684 | 0.72 | F10 (0.59) | F10CCR2PLA2G10 | |
| SCHEMBL6433289 | 0.72 | NOD2 (0.67) | F10CCR2KMT2APLA2G10POLB | |
| SCHEMBL6432780 | 0.72 | F10 (0.56) | F10CCR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |