Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.82 |
| ▸ | F2 | P00734 | 3/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | CCR2 | P41597 | 1/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.54 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6432795 | 0.90 | F10 (0.68) | F10F2SRD5A2CCR2LTB4R | |
| Iodide SCHEMBL6432604 | 0.88 | F10 (0.98) | F10F2 | |
| Acetic Acid SCHEMBL7717345 | 0.88 | F10 (0.95) | F10F2 | |
| SCHEMBL7432408 | 0.87 | F10 (0.70) | F10F2SRD5A2 | |
| SCHEMBL6432819 | 0.84 | F10 (0.84) | F10F2CCR2PLA2G10 | |
| SCHEMBL3967516 | 0.82 | CCR2 (0.73) | F10SRD5A2CCR2LTB4RLTB4R2 | |
| SCHEMBL30249718 | 0.82 | F10 (0.89) | F10F2 | |
| SCHEMBL4316499 | 0.82 | F10 (0.89) | F10F2 | |
| SCHEMBL6433216 | 0.82 | F10 (0.78) | F10F2CCR2PLA2G10 | |
| SCHEMBL7429228 | 0.81 | F10 (0.69) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042287-B1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |