Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429712 | 0.93 | TSHR (0.46) | ALOX15TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL7686601 | 0.74 | TRPV1 (0.46) | ALOX15TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL7372297 | 0.72 | SMN1; SMN2 (0.48) | TSHRALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7682371 | 0.69 | FABP1 (0.46) | ALOX15TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL7426048 | 0.68 | KAT6A (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL14313616 | 0.67 | ALOX15 (0.74) | ALOX15TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL7317448 | 0.66 | GAA (0.59) | TSHRALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5622664 | 0.66 | SMN1; SMN2 (0.64) | ALOX15TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9239543 | 0.65 | ALOX15 (0.71) | ALOX15TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL7468069 | 0.64 | PPARG (0.64) | ALOX15TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073632-A1 | SUBSTITUTED BENZAMIDES, THEIR PRODUCTION AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054293-A1 | SUBSTITUTED BENZAMIDES, THEIR PRODUCTION AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-28 | — | — | WO | disclosed |