Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | PKLR | P30613 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786970 | 0.72 | FABP1 (0.49) | SMN1; SMN2GAAKMT2AALDH1A1MEN1 | |
| SCHEMBL7786973 | 0.72 | FABP1 (0.49) | SMN1; SMN2GAAKMT2AALDH1A1MEN1 | |
| SCHEMBL7782131 | 0.72 | MEN1 (0.57) | GAANPSR1MAPTKMT2AALDH1A1 | |
| SCHEMBL7782132 | 0.72 | MEN1 (0.57) | GAANPSR1MAPTKMT2AALDH1A1 | |
| SCHEMBL7429231 | 0.72 | ALOX15 (0.44) | SMN1; SMN2GAANPSR1MAPTKMT2A | |
| SCHEMBL7429712 | 0.71 | TSHR (0.46) | SMN1; SMN2GAANPSR1MAPTKMT2A | |
| SCHEMBL7317448 | 0.69 | GAA (0.59) | SMN1; SMN2GAAMAPTKMT2AALDH1A1 | |
| SCHEMBL7786993 | 0.67 | FABP1 (0.50) | SMN1; SMN2GAAKMT2AALDH1A1MEN1 | |
| SCHEMBL7786996 | 0.67 | FABP1 (0.50) | SMN1; SMN2GAAKMT2AALDH1A1MEN1 | |
| SCHEMBL27995018 | 0.67 | GAA (0.52) | SMN1; SMN2GAANPSR1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944584-A1 | BENZAMIDOALDEHYDES AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998023581-A1 | BENZAMIDOALDEHYDES AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-04 | — | — | WO | disclosed |