Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609206 | 0.84 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL7050093 | 0.81 | PDE4A (0.48) | ALDH1A1KDM4EMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL7420398 | 0.81 | PDE4D (0.39) | — | |
| SCHEMBL7425562 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL6605271 | 0.75 | KMT2A (0.41) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL6606907 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL6605220 | 0.74 | KMT2A (0.42) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL7432082 | 0.73 | UTS2R (0.37) | MAPT | |
| SCHEMBL7429380 | 0.73 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL7055317 | 0.71 | MAPT (0.43) | ALDH1A1KDM4EMAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054884-A1 | BENZOFURAN-4-CARBOXAMIDES AND THEIR THERAPEUTIC USE | Darwin Discovery Limited (GB) | 2000-11-29 | — | — | EP | disclosed |
| US-6066657-A | Benzofuran-4-carboxamides and their therapeutic use | DARWIN DISCOVERY, LTD. (GB) | 2000-05-23 | — | — | US | disclosed |
| WO-1999040085-A1 | BENZOFURAN-4-CARBOXAMIDES AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LIMITED (GB) | 1999-08-12 | — | — | WO | disclosed |