Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055321 | 0.83 | MAPT (0.43) | ALDH1A1KMT2ARAB9AL3MBTL1MAPT | |
| SCHEMBL7055317 | 0.83 | MAPT (0.43) | ALDH1A1KMT2ARAB9AL3MBTL1MAPT | |
| SCHEMBL7055316 | 0.83 | MAPT (0.43) | ALDH1A1KMT2ARAB9AL3MBTL1MAPT | |
| SCHEMBL7050093 | 0.80 | PDE4A (0.48) | ALDH1A1KMT2ARAB9AL3MBTL1MAPT | |
| SCHEMBL6605220 | 0.80 | KMT2A (0.42) | ALDH1A1KMT2AMAPTKDM4EHPGD | |
| SCHEMBL6606907 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL6609206 | 0.79 | ALDH1A1 (0.45) | ALDH1A1KMT2ARAB9AL3MBTL1MAPT | |
| SCHEMBL7050590 | 0.79 | RAB9A (0.43) | ALDH1A1KMT2ARAB9AL3MBTL1MAPT | |
| SCHEMBL7423948 | 0.78 | PDE4D (0.48) | ALDH1A1MAPTKDM4ELMNAPDE4A | |
| SCHEMBL7429380 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KMT2AMAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054884-A1 | BENZOFURAN-4-CARBOXAMIDES AND THEIR THERAPEUTIC USE | Darwin Discovery Limited (GB) | 2000-11-29 | — | — | EP | disclosed |
| US-6066657-A | Benzofuran-4-carboxamides and their therapeutic use | DARWIN DISCOVERY, LTD. (GB) | 2000-05-23 | — | — | US | disclosed |
| WO-1999040085-A1 | BENZOFURAN-4-CARBOXAMIDES AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LIMITED (GB) | 1999-08-12 | — | — | WO | disclosed |