Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 11/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydrocinnamaldehyde SCHEMBL1335 | 0.87 | ADH1B (0.50) | GPR52KEAP1ALDH1A1HDAC3MAPK1 | |
| Dihydrocinnamaldehyde SCHEMBL5791873 | 0.85 | ADH1B (0.48) | GPR52KEAP1ALDH1A1HDAC3MAPK1 | |
| Dihydrocinnamaldehyde SCHEMBL11053817 | 0.85 | ADH1B (0.48) | GPR52KEAP1ALDH1A1HDAC3MAPK1 | |
| Dihydrocinnamaldehyde SCHEMBL19810527 | 0.85 | ADH1B (0.48) | GPR52KEAP1ALDH1A1HDAC3MAPK1 | |
| Dihydrocinnamaldehyde SCHEMBL11053918 | 0.85 | ADH1B (0.48) | GPR52KEAP1ALDH1A1HDAC3MAPK1 | |
| Dihydrocinnamaldehyde SCHEMBL3689341 | 0.82 | GPR52 (0.46) | GPR52KEAP1ALDH1A1HDAC3MAPK1 | |
| Dihydrocinnamaldehyde SCHEMBL28677758 | 0.82 | GPR52 (0.46) | GPR52KEAP1ALDH1A1HDAC3MAPK1 | |
| Dihydrocinnamaldehyde SCHEMBL29052009 | 0.82 | TDP1 (0.48) | GPR52KEAP1ALDH1A1HDAC3MAPK1 | |
| Dihydrocinnamaldehyde SCHEMBL1092744 | 0.81 | MAOB (0.48) | GPR52KEAP1ALDH1A1HDAC3MAPK1 | |
| Dihydrocinnamaldehyde SCHEMBL8109306 | 0.79 | ADH1B (0.43) | GPR52KEAP1ALDH1A1ADRA1ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127049-A1 | BRIDGED HETEROCYCLIC DERIVATIVES | GPI NIL Holdings, Inc. (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-1105125-A2 | USE OF SULFONAMIDES FOR TREATING VISION AND MEMORY DISORDERS | GPI NIL Holdings, Inc. (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-1083876-A1 | SMALL MOLECULE SULFONAMIDE HAIR GROWTH COMPOSITIONS AND USES | GPI NIL Holdings, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-2000016603-A2 | BRIDGED HETEROCYCLIC DERIVATIVES | GPI NIL HOLDINGS, INC. (US) | 2000-03-30 | — | — | WO | disclosed |
| WO-2000009104-A2 | USE OF SULFONAMIDES FOR TREATING VISION AND MEMORY DISORDERS | GPI NHL HOLDINGS, INC. (US) | 2000-02-24 | — | — | WO | disclosed |
| WO-1999062490-A1 | SMALL MOLECULE SULFONAMIDE HAIR GROWTH COMPOSITIONS AND USES | GPI NIL HOLDINGS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |