Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430661 | 0.89 | ALDH1A1 (0.53) | KMT2AMEN1POLBALDH1A1RAB9A | |
| SCHEMBL7433270 | 0.84 | RAB9A (0.49) | KMT2AMEN1POLBALDH1A1RAB9A | |
| SCHEMBL7427610 | 0.83 | NPSR1 (0.48) | KMT2AMEN1POLBALDH1A1RAB9A | |
| SCHEMBL7429898 | 0.83 | RAB9A (0.49) | KMT2AMEN1POLBALDH1A1RAB9A | |
| SCHEMBL7441514 | 0.81 | RAB9A (0.46) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL7433994 | 0.80 | RAB9A (0.53) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL7441475 | 0.77 | RAB9A (0.50) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL7429429 | 0.75 | KMT2A (0.50) | KMT2AMEN1POLBALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL7430571 | 0.74 | ALDH1A1 (0.46) | KMT2AMEN1POLBALDH1A1RAB9A | |
| SCHEMBL7437001 | 0.74 | CREBBP (0.46) | KMT2AMEN1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |