Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.55 |
| ▸ | HTR4 | Q13639 | 16/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL27529758 | 1.00 | ELANE (0.55) | ELANEHTR4SCN9ACYP3A4KCNH2 | |
| SCHEMBL4777015 | 0.95 | ELANE (0.55) | ELANEHTR4SCN9AKCNH2KMT2A | |
| Hydrochloric Acid SCHEMBL27569092 | 0.94 | ELANE (0.54) | ELANEHTR4SCN9AKCNH2KMT2A | |
| SCHEMBL29805676 | 0.84 | HTR4 (0.55) | HTR4CYP3A4KMT2AHTR2A | |
| SCHEMBL1832626 | 0.84 | HTR4 (0.55) | HTR4CYP3A4KMT2AHTR2A | |
| Hydrochloric Acid SCHEMBL1405875 | 0.83 | HTR4 (0.54) | HTR4KCNH2KMT2AHTR2A | |
| SCHEMBL17324791 | 0.81 | HTR4 (0.55) | HTR4KCNH2KMT2AHTR2A | |
| SCHEMBL8875819 | 0.81 | ELANE (0.50) | ELANEHTR4SCN9AKMT2A | |
| SCHEMBL28253854 | 0.80 | ELANE (0.55) | ELANEHTR4SCN9AKMT2A | |
| SCHEMBL17321411 | 0.80 | HTR4 (0.54) | HTR4KCNH2KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999017772-A1 | 5HT4 AGONISTS AND ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1999-04-15 | — | — | WO | disclosed |