Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030220 | 0.72 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNA7CHRM5CHRM3 | |
| SCHEMBL25295829 | 0.72 | — | — | |
| SCHEMBL1030421 | 0.72 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNA7CHRM5CHRM3 | |
| SCHEMBL1031980 | 0.72 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNA7CHRM5CHRM3 | |
| SCHEMBL30824585 | 0.71 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNA7CHRM5CHRM3 | |
| SCHEMBL3926825 | 0.71 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNA7CHRM5CHRM3 | |
| SCHEMBL29977611 | 0.71 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNA7CHRM5CHRM3 | |
| SCHEMBL105810 | 0.71 | HRH4 (0.39) | MEN1KMT2A | |
| SCHEMBL20707 | 0.71 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNA7CHRM5CHRM3 | |
| SCHEMBL3925606 | 0.71 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNA7CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244836-B1 | TRIPEPTIDE DERIVATIVES | Dainippon Pharmaceutical Co., Ltd. (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-4826814-A | INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-05-02 | — | — | US | disclosed |