Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280848 | 0.90 | LMNA (0.63) | GAALMNAAPPKMT2AALDH1A1 | |
| SCHEMBL9556448 | 0.79 | GAA (0.43) | GAALMNAAPPKMT2AALDH1A1 | |
| SCHEMBL7430228 | 0.77 | BCHE (0.44) | GAALMNAHPGD | |
| SCHEMBL7305185 | 0.75 | KMT2A (0.47) | LMNAKMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL7539920 | 0.74 | KMT2A (0.47) | GAALMNAKMT2AALDH1A1HPGD | |
| SCHEMBL7539935 | 0.74 | KMT2A (0.47) | GAALMNAKMT2AALDH1A1HPGD | |
| SCHEMBL14598352 | 0.74 | LMNA (0.58) | GAALMNAAPP | |
| SCHEMBL12935849 | 0.73 | GAA (0.48) | GAALMNAKMT2AALDH1A1KDM4E | |
| SCHEMBL127790 | 0.72 | HPGD (0.60) | GAALMNAKMT2AALDH1A1HPGD | |
| SCHEMBL24486834 | 0.71 | LMNA (0.64) | GAALMNAAPPKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416393-A1 | Peptidyl difluorodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |