Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CPA1 | P15085 | 3/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | CPA3 | P15088 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280854 | 0.90 | CPA1 (0.53) | BCHEACHELMNACYP1A2CPA1 | |
| SCHEMBL7299196 | 0.82 | MMP2 (0.44) | — | |
| SCHEMBL7436937 | 0.82 | MME (0.41) | CYP1A2CPA1CPB1CPA3CPB2 | |
| SCHEMBL7305187 | 0.78 | REN (0.45) | LMNACYP1A2CPA1CPB1CPA3 | |
| SCHEMBL7539929 | 0.77 | NPC1 (0.52) | CYP1A2CYP2D6 | |
| SCHEMBL7539925 | 0.77 | NPC1 (0.52) | CYP1A2CYP2D6 | |
| SCHEMBL7430223 | 0.77 | GAA (0.60) | LMNAHPGDGAA | |
| SCHEMBL7438742 | 0.76 | REN (0.44) | CYP1A2CPA1CPB1CPA3CPB2 | |
| Hydrochloric Acid SCHEMBL10449746 | 0.76 | CPA1 (0.55) | CYP1A2CPA1CPB1CPA3CPB2 | |
| SCHEMBL7536749 | 0.76 | HRH4 (0.41) | LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416393-A1 | Peptidyl difluorodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |