Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.44 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.44 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23448763 | 0.87 | HRH3 (0.44) | RIPK1ALDH1A1HDAC6HTR2CSLC6A4 | |
| SCHEMBL1935308 | 0.85 | PPARG (0.46) | RIPK1ALDH1A1HTR2CSLC6A4 | |
| SCHEMBL25546128 | 0.85 | HSP90AA1 (0.43) | RIPK1ALDH1A1HTR2CSLC6A4LIPE | |
| SCHEMBL2229917 | 0.85 | MTOR (0.48) | RIPK1ALDH1A1HTR2CSLC6A4 | |
| SCHEMBL14326997 | 0.84 | TAAR1 (0.50) | RIPK1TDP1KDM1AHDAC8HDAC6 | |
| SCHEMBL19950236 | 0.84 | CLK1 (0.45) | RIPK1GRM2KMT2AHTR2CSLC6A4 | |
| SCHEMBL1935742 | 0.84 | AKT1 (0.43) | RIPK1ALDH1A1MAPTHTR2CSLC6A4 | |
| SCHEMBL8139521 | 0.84 | TPSAB1 (0.47) | RIPK1ALDH1A1KMT2AHTR2CSLC6A4 | |
| SCHEMBL5726780 | 0.84 | HTR2C (0.41) | RIPK1ALDH1A1HTR2CSLC6A4 | |
| SCHEMBL30264860 | 0.84 | ALDH1A1 (0.57) | RIPK1ALDH1A1LMNANR1D1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078410-A1 | COMPOUND HAVING ACTIVITY OF DEGRADING GSPT1 AND APPLICATION THEREOF | 上海美志医药科技有限公司 | 2023-05-11 | — | — | WO | disclosed |
| EP-0609625-A1 | Inhibitors of HIV protease useful for the treatment of AIDS | ELI LILLY AND COMPANY (US) | 1994-08-10 | — | — | EP | disclosed |