Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | ME2 | P23368 | 1/20 | 0.63 |
| ▸ | ME1 | P48163 | 1/20 | 0.63 |
| ▸ | ME3 | Q16798 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | GPR183 | P32249 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528958 | 0.98 | HPGD (0.70) | HPGDSMN1; SMN2NPC1GFERATM | |
| SCHEMBL4671683 | 0.86 | GFER (0.61) | HPGDSMN1; SMN2NPC1GFERATM | |
| SCHEMBL26100265 | 0.85 | HPGD (0.55) | HPGDSMN1; SMN2NPC1GFERATM | |
| SCHEMBL22217034 | 0.85 | SMN1; SMN2 (0.67) | HPGDSMN1; SMN2NPC1GFERATM | |
| SCHEMBL24352145 | 0.84 | KMT2A (0.72) | NPC1GFERATMME2ME1 | |
| SCHEMBL15134817 | 0.84 | MAPT (0.68) | HPGDSMN1; SMN2GFERATMME2 | |
| SCHEMBL654067 | 0.84 | GFER (0.60) | HPGDSMN1; SMN2NPC1GFERATM | |
| SCHEMBL26099857 | 0.83 | MAPT (0.53) | HPGDSMN1; SMN2NPC1GFERATM | |
| SCHEMBL15985154 | 0.83 | SMN1; SMN2 (0.69) | HPGDSMN1; SMN2NPC1ME2ME1 | |
| SCHEMBL27405797 | 0.82 | NPC1 (0.70) | HPGDSMN1; SMN2NPC1ME2ME1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |
| EP-1071669-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2001-01-31 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999054313-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-28 | — | — | WO | disclosed |