Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | FAAH | O00519 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | MGLL | Q99685 | 1/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | ME2 | P23368 | 1/20 | 0.62 |
| ▸ | ME1 | P48163 | 1/20 | 0.62 |
| ▸ | ME3 | Q16798 | 1/20 | 0.62 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | PHGDH | O43175 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430480 | 0.84 | HPGD (0.67) | KMT2AMAPTALDH1A1GFERATM | |
| SCHEMBL9557082 | 0.84 | FKBP1A (0.72) | KMT2AMAPTFAAHALDH1A1MGLL | |
| SCHEMBL26546711 | 0.83 | SMN1; SMN2 (0.57) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL15650184 | 0.83 | MAPT (0.68) | KMT2AMAPTALDH1A1FKBP1AHTT | |
| SCHEMBL5257247 | 0.83 | MAPT (0.68) | KMT2AMAPTFKBP1AAKR1C3PHGDH | |
| SCHEMBL10174349 | 0.83 | MAPT (0.68) | KMT2AMAPTFAAHALDH1A1MGLL | |
| SCHEMBL2798761 | 0.83 | L3MBTL1 (0.72) | KMT2AMAPTALDH1A1MEN1HTT | |
| SCHEMBL9528958 | 0.83 | HPGD (0.70) | KMT2AMAPTALDH1A1GFERATM | |
| SCHEMBL1516144 | 0.83 | MAPT (0.82) | KMT2AMAPTALDH1A1ME2ME1 | |
| SCHEMBL8704220 | 0.83 | ALDH1A1 (0.61) | KMT2AMAPTFAAHALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220111367-A1 | HYDROGENATION CATALYST FOR USE IN HYDROGENATING AMIDE COMPOUND AND METHOD FOR PRODUCING AMINE COMPOUND USING SAME | OSAKA UNIVERSITY (JP) | 2022-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220111367-A1 | HYDROGENATION CATALYST FOR USE IN HYDROGENATING AMIDE COMPOUND AND METHOD FOR PRODUCING AMINE COMPOUND USING SAME | SUV39H2, SUV39H1, HRH3 | KMT2A 145/4885MAPT 1731/4885FAAH 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.