Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426578 | 0.93 | CSNK1D (0.46) | EPHX2CSNK1DMAPTRAB9ANPC1 | |
| SCHEMBL7429855 | 0.92 | CSNK1D (0.49) | CSNK1DMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7657273 | 0.82 | EPHX2 (0.49) | EPHX2POLBKDM4EMEN1ALDH1A1 | |
| SCHEMBL7428151 | 0.80 | CSF1R (0.50) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL7665064 | 0.76 | LCK (0.48) | MAPTRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL7475860 | 0.74 | RAB9A (0.48) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL6598330 | 0.73 | P2RY14 (0.49) | EPHX2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6594493 | 0.71 | HDAC6 (0.52) | EPHX2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7665075 | 0.71 | MAPT (0.42) | CSNK1DMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7432860 | 0.70 | MAPT (0.59) | CSNK1DMAPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133484-A2 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | AstraZeneca AB (SE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000005223-A2 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | ASTRAZENECA AB (SE) | 2000-02-03 | — | — | WO | disclosed |