Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.52 |
| ▸ | HRH2 | P25021 | 2/20 | 0.52 |
| ▸ | NAMPT | P43490 | 3/20 | 0.48 |
| ▸ | QPCT | Q16769 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353954 | 0.87 | HRH4 (0.52) | HRH4HRH2NAMPTQPCT | |
| SCHEMBL8915165 | 0.85 | NAMPT (0.52) | NAMPTQPCTKCNJ11 | |
| SCHEMBL8915162 | 0.85 | NAMPT (0.52) | NAMPTQPCTKCNJ11 | |
| SCHEMBL8921935 | 0.83 | NAMPT (0.57) | NAMPTQPCTKCNJ11 | |
| SCHEMBL8921940 | 0.83 | NAMPT (0.57) | NAMPTQPCTKCNJ11 | |
| SCHEMBL7356849 | 0.83 | NAMPT (0.60) | HRH4HRH2NAMPTQPCTKCNJ11 | |
| SCHEMBL8918937 | 0.82 | HRH4 (0.48) | HRH4HRH2NAMPTQPCTKCNJ11 | |
| SCHEMBL8918934 | 0.82 | HRH4 (0.48) | HRH4HRH2NAMPTQPCTKCNJ11 | |
| SCHEMBL7430606 | 0.78 | POLB (0.53) | HRH4HRH2POLB | |
| SCHEMBL7423091 | 0.78 | NAMPT (0.59) | HRH4HRH2NAMPTQPCTKCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741708-A1 | CYANOGUANIDINES AS K-CHANNEL BLOCKERS | PHARMACIA & UPJOHN COMPANY (US) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995020579-A1 | CYANOGUANIDINES AS K-CHANNEL BLOCKERS | PHARMACIA & UPJOHN COMPANY (US) | 1995-08-03 | — | — | WO | disclosed |