Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane Carboxamide SCHEMBL6831864 | 0.98 | CES2 (0.42) | KDM4EKMT2AMAPTATMCYP2D6 | |
| Trifluoroacetic Acid SCHEMBL28336846 | 0.95 | KDM4E (0.42) | KDM4EKMT2AMAPTATMCYP2D6 | |
| Trifluoroacetic Acid SCHEMBL4446964 | 0.91 | SMN1; SMN2 (0.39) | KDM4EKMT2AMAPTATMCYP2D6 | |
| Bicarbonate SCHEMBL9032315 | 0.83 | KDM4E (0.50) | KDM4EKMT2AMAPTATMCYP2D6 | |
| Trifluoroacetic Acid SCHEMBL3154223 | 0.83 | GAA (0.35) | KDM4EKMT2AMAPTATMCYP2D6 | |
| SCHEMBL176610 | 0.83 | — | — | |
| Trifluoroacetic Acid SCHEMBL27702588 | 0.81 | CES2 (0.42) | CES2CES1GAASMN1; SMN2TSHR | |
| Trifluoroacetic Acid SCHEMBL5722383 | 0.81 | TSHR (0.42) | CES2CES1GAASMN1; SMN2TSHR | |
| Trifluoroacetic Acid SCHEMBL3377545 | 0.81 | GABRP (0.50) | KDM4EKMT2AMAPTATMCYP2D6 | |
| Trifluoroacetic Acid SCHEMBL3624786 | 0.81 | GAA (0.34) | KDM4EKMT2AMAPTATMCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4480541-A2 | KETONE INHIBITORS OF LYSINE GINGIPAIN | Lighthouse Pharmaceuticals, Inc. (US) | 2024-12-25 | — | — | EP | disclosed |
| EP-1263755-A2 | CYCLIC BETA-AMINO ACID DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEASES AND TNF-ALPHA | Bristol-Myers Squibb Pharma Company (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001070673-A2 | CYCLIC β-AMINO ACID DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEASES AND TNF-$g(a) | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |