Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | SI | P14410 | 1/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL452234 | 0.84 | GAA (0.54) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL19236955 | 0.83 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL3840221 | 0.83 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5595600 | 0.83 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL11193578 | 0.81 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL7721965 | 0.81 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL21578650 | 0.81 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL13774331 | 0.81 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL28550238 | 0.79 | — | — | |
| SCHEMBL10124278 | 0.79 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105534893-A | Stable Azastron hydrochloride pharmaceutical composition for injection | SICHUAN SUNNYHOPE PHARMACEUTICAL CO LTD | 2016-05-04 | — | — | CN | disclosed |
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |
| US-4923865-A | Substituted 1-(1H-imidazol-4-yl)alkyl-benzamides as anti-ischemics and as alpha-2-adrenergic receptor agonists | U C B SOCIETE ANONYME (BE) | 1990-05-08 | — | — | US | disclosed |
| US-4167448-A | AMASTATINS A1, A2, A3, B1 AND B2 PRODUCED BY AEROBIC CULTIVATION OF STREPTOMYCES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1979-09-11 | — | — | US | disclosed |
| US-4126606-A | CONTAINING VALINE, AMASTATINS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1978-11-21 | — | — | US | disclosed |