Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PPID | Q08752 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13774331 | 1.00 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27816766 | 0.98 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL19236955 | 0.86 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10124278 | 0.86 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL3840221 | 0.86 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2039271 | 0.84 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10184338 | 0.84 | KDM4E (0.44) | GAAALDH1A1HTTCYP2D6CYP2C9 | |
| SCHEMBL10184357 | 0.83 | HTT (0.42) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL13774329 | 0.83 | HTT (0.42) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL452234 | 0.83 | GAA (0.54) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110950805-A | Fluorouracil prodrug with low cytotoxicity as well as preparation method and application thereof | 黑龙江福和制药集团股份有限公司 | 2020-04-03 | — | — | CN | disclosed |
| US-9316911-B2 | Actinic-ray- or radiation-sensitive resin composition, actinic-ray- or radiation-sensitive film therefrom and method of forming pattern using the composition | FUJIFILM CORPORATION (JP) | 2016-04-19 | — | — | US | disclosed |
| US-9316911-B2 | Actinic-ray- or radiation-sensitive resin composition, actinic-ray- or radiation-sensitive film therefrom and method of forming pattern using the composition | FUJIFILM CORPORATION (JP) | 2016-04-19 | — | — | US | disclosed |
| US-8772301-B2 | Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof | SUNOVION PHARMACEUTICALS, INC. (US) | 2014-07-08 | — | — | US | disclosed |
| CN-101891669-B | 3-substituted cyclopropane carbonyl pyrrolidine-2,4-diketone and herbicidal activity thereof | UNIV NANKAI | 2013-03-27 | — | — | CN | disclosed |
| US-20130004741-A1 | ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC-RAY- OR RADIATION-SENSITIVE FILM THEREFROM AND METHOD OF FORMING PATTERN USING THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2013-01-03 | — | — | US | disclosed |
| US-20130004741-A1 | ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC-RAY- OR RADIATION-SENSITIVE FILM THEREFROM AND METHOD OF FORMING PATTERN USING THE COMPOSITION | FUJIFILM CORPORATION (JP) | 2013-01-03 | — | — | US | disclosed |
| US-20120009147-A1 | 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-01-12 | — | — | US | disclosed |
| CN-101891669-A | 3-substituted cyclopropane carbonyl pyrrolidine-2,4-diketone and herbicidal activity thereof | UNIV NANKAI | 2010-11-24 | — | — | CN | disclosed |
| CN-100486965-C | 3-acyl-pyrrolidine-2,4-diketo compound and herbicidal activity | UNIV NANKAI (CN) | 2009-05-13 | — | — | CN | disclosed |
| CN-1676515-A | 3-acyl-pyrrolidine-2,4-diketo compound and herbicidal activity | UNIV NANKAI (CN) | 2005-10-05 | — | — | CN | disclosed |
| WO-2002081413-A2 | ONE DIMENSIONAL UNICHEMO PROTECTION (UCP) IN ORGANIC SYNTHESIS | CARLSBERG A/S (DK) | 2002-10-17 | — | — | WO | disclosed |
| US-20020146684-A1 | One dimensional unichemo protection (UCP) in organic synthesis | CARLSBERG A/S (DK) | 2002-10-10 | — | — | US | disclosed |
| US-4421693-A | INSECTICIDES, MITICIDES OR NEMATOCIDES | OTSUKA CHEMICAL CO., LTD. (JP) | 1983-12-20 | — | — | US | disclosed |
| US-4413005-A | 2,3-DIHYDRO-2,2-DIMETHYLBENZOFURAN-7-YL DERIVATIVES | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) | 1983-11-01 | — | — | US | disclosed |
| US-3968214-A | 5-Methylthio-pyrimidine vasodilators | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009147-A1 | 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | PNP, NSUN2, CDA | GAA 1129/4885MGAM 450/4885SI 556/4885 |
| US-20020146684-A1 | One dimensional unichemo protection (UCP) in organic synthesis | UMPS, UROD, URB2 | GAA 3620/4885MGAM 3320/4885SI 2684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.