Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19236955 | 1.00 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL13774331 | 0.86 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL7721965 | 0.86 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27816766 | 0.84 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10124278 | 0.84 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL7430700 | 0.83 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2039271 | 0.82 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL5681183 | 0.82 | GAA (0.42) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL452234 | 0.81 | GAA (0.54) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL29496889 | 0.81 | L3MBTL1 (0.49) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362845-B1 | New process for the synthesis of N-((S)-1-carboxybutyl)-(S)-alanine esters and their use in the synthesis of perindopril | SERVIER LAB (FR) | 2009-10-14 | — | — | EP | disclosed |
| US-7361757-B2 | Method for synthesizing esters of N-[(S)-1-carboxybutyl]-(S)-alanine and use thereof for synthesizing perindopril | LES LABORATOIRES SERVIER (FR) | 2008-04-22 | — | — | US | disclosed |
| US-20060252958-A1 | Novel method for synthesizing esters of n-[(s)-1-carboxybutyl]-(s)-alanine and use thereof for synthesizing perindopril | LES LABORATOIRES SERVIER (FR) | 2006-11-09 | — | — | US | disclosed |
| WO-2005023755-A1 | NOVEL METHOD FOR SYNTHESIZING ESTERS OF N-[(S)-1-CARBOXYBUTYL]-(S)-ALANINE AND USE THEREOF FOR SYNTHESIZING PERINDOPRIL | LES LABORATOIRES SERVIER (FR) | 2005-03-17 | — | — | WO | disclosed |
| EP-1362845-A2 | New process for the synthesis of N-((S)-1-carboxybutyl)-(S)-alanine esters and their use in the synthesis of perindopril | Les Laboratoires Servier (FR) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252958-A1 | Novel method for synthesizing esters of n-[(s)-1-carboxybutyl]-(s)-alanine and use thereof for synthesizing perindopril | ACE, AGT, AGTR1 | GAA 1011/4885MGAM 1209/4885SI 541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.