Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KCNB1 | Q14721 | 3/20 | 0.41 |
| ▸ | KCNB2 | Q92953 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438002 | 0.86 | KDM4C (0.50) | GAAALDH1A1ALOX15KDM4EMCL1 | |
| SCHEMBL7432272 | 0.85 | ALDH1A1 (0.46) | GAAALDH1A1KDM4EMCL1BCL2A1 | |
| SCHEMBL7430294 | 0.85 | GAA (0.46) | GAAALDH1A1ALOX15KDM4EKCNB1 | |
| SCHEMBL7435750 | 0.84 | KMT2A (0.47) | GAAALDH1A1ALOX15KDM4EMCL1 | |
| SCHEMBL7428540 | 0.83 | HDAC3 (0.41) | GAAALDH1A1MCL1BCL2A1HDAC3 | |
| SCHEMBL7431831 | 0.80 | KDM4E (0.60) | GAAALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL7435487 | 0.80 | HDAC3 (0.49) | GAAALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL7432797 | 0.79 | SMN1; SMN2 (0.51) | GAAALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL7439282 | 0.78 | KMT2A (0.53) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL7433961 | 0.76 | ABCC1 (0.47) | GAAALDH1A1KDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |