Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | KCNB1 | Q14721 | 3/20 | 0.44 |
| ▸ | KCNB2 | Q92953 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430848 | 0.85 | GAA (0.42) | GAAALDH1A1ALOX15KCNB1KCNB2 | |
| SCHEMBL7426875 | 0.83 | KDM4C (0.52) | GAAALDH1A1ALOX15MCL1BCL2A1 | |
| SCHEMBL7426816 | 0.82 | ALDH1A1 (0.47) | GAAALDH1A1MCL1BCL2A1MAPT | |
| SCHEMBL7433435 | 0.81 | KMT2A (0.52) | GAAALDH1A1ALOX15MCL1BCL2A1 | |
| SCHEMBL7428063 | 0.80 | MAPT (0.44) | GAAALDH1A1MCL1BCL2A1MAPT | |
| SCHEMBL7432052 | 0.77 | KDM4E (0.65) | GAAALDH1A1MCL1BCL2A1MAPT | |
| SCHEMBL7439101 | 0.76 | CA12 (0.52) | GAAALDH1A1MAPTHTT | |
| SCHEMBL7436440 | 0.76 | SMN1; SMN2 (0.56) | GAAALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL7434461 | 0.75 | SMN1; SMN2 (0.55) | GAAALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL4657193 | 0.74 | FFAR1 (0.52) | GAAALDH1A1ALOX15MCL1BCL2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |