Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 11/20 | 0.61 |
| ▸ | CTSD | P07339 | 3/20 | 0.60 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6449655 | 0.94 | CTSD (0.66) | BACE1CTSDKLK5 | |
| SCHEMBL15095216 | 0.93 | CTSD (0.67) | BACE1CTSDKLK5 | |
| SCHEMBL6447745 | 0.93 | CTSD (0.66) | BACE1CTSDKLK5 | |
| SCHEMBL6448985 | 0.92 | CTSD (0.68) | BACE1CTSD | |
| SCHEMBL6454320 | 0.92 | CTSD (0.68) | BACE1CTSD | |
| SCHEMBL7270278 | 0.92 | CTSD (0.67) | BACE1CTSDKLK5 | |
| SCHEMBL6446462 | 0.91 | CTSD (0.56) | BACE1CTSDKLK5 | |
| SCHEMBL6449617 | 0.91 | CTSD (0.68) | BACE1CTSD | |
| SCHEMBL7268574 | 0.91 | CTSD (0.68) | BACE1CTSD | |
| SCHEMBL7443260 | 0.88 | CTSD (0.59) | BACE1CTSDKLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018866-A2 | 1,4-DIAMINO-2,3-DIHYDROXYBUTANES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-12-12 | — | — | WO | claimed |
| EP-0665215-A1 | 1,4-Diamino-2,3-dihydroxybutanes | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-08-02 | — | — | EP | disclosed |