Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.41 |
| ▸ | TNF | P01375 | 4/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431118 | 1.00 | MAPT (0.45) | MAPTTSHRHSD17B10HPGDTAAR1 | |
| SCHEMBL7432248 | 0.95 | MAPT (0.45) | MAPTTSHRHSD17B10HPGDTAAR1 | |
| SCHEMBL7432253 | 0.95 | MAPT (0.45) | MAPTTSHRHSD17B10HPGDTAAR1 | |
| SCHEMBL7486145 | 0.94 | MAPT (0.42) | MAPTTSHRHSD17B10HPGDTAAR1 | |
| SCHEMBL7438880 | 0.94 | MAPT (0.42) | MAPTTSHRHSD17B10HPGDTAAR1 | |
| SCHEMBL7435647 | 0.93 | NOD1 (0.47) | MAPTTSHRHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL7435636 | 0.93 | NOD1 (0.47) | MAPTTSHRHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL7433074 | 0.92 | ITGB3 (0.42) | MAPTTSHRHSD17B10HPGDTAAR1 | |
| SCHEMBL7395295 | 0.92 | MAPT (0.44) | MAPTTSHRHSD17B10HPGDTAAR1 | |
| SCHEMBL7394455 | 0.92 | MAPT (0.44) | MAPTTSHRHSD17B10HPGDTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |