Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 6/20 | 0.40 |
| ▸ | CES2 | O00748 | 7/20 | 0.39 |
| ▸ | CES1 | P23141 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28139971 | 0.98 | NAAA (0.48) | NAAAFAAHCES2CES1CA2 | |
| SCHEMBL27493006 | 0.98 | NAAA (0.48) | NAAAFAAHCES2CES1CA2 | |
| SCHEMBL8364456 | 0.98 | NAAA (0.48) | NAAAFAAHCES2CES1CA2 | |
| SCHEMBL28050419 | 0.96 | NAAA (0.47) | NAAAFAAHCES2CES1CA2 | |
| SCHEMBL6173099 | 0.94 | NAAA (0.42) | NAAAFAAHCES2CES1CA2 | |
| SCHEMBL18126438 | 0.94 | NAAA (0.35) | NAAAFAAH | |
| Propionic Acid SCHEMBL29000721 | 0.93 | NAAA (0.44) | NAAAFAAH | |
| SCHEMBL18126488 | 0.91 | NAAA (0.39) | NAAAFAAHCES2CES1CA2 | |
| SCHEMBL18126512 | 0.91 | NAAA (0.39) | NAAAFAAHCES2CES1CA2 | |
| SCHEMBL32679584 | 0.88 | CES2 (0.44) | FAAHCES2CES1CA2DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006215-A1 | 3-ARYLSULFONYL-2-HYDROXY-2-METHYLPROPANOIC ACID DERIVATES | PHARMACIA ITALIA S.P.A. (IT) | 2002-01-24 | — | — | WO | claimed |
| WO-2002006215-A1 | 3-ARYLSULFONYL-2-HYDROXY-2-METHYLPROPANOIC ACID DERIVATES | PHARMACIA ITALIA S.P.A. (IT) | 2002-01-24 | — | — | WO | disclosed |