Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 5/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9545040 | 0.88 | MTNR1A (0.56) | PRMT5MTNR1AMTNR1BGRIN2BMEN1 | |
| Hydrochloric Acid SCHEMBL9545036 | 0.88 | MTNR1A (0.56) | PRMT5MTNR1AMTNR1BGRIN2BMEN1 | |
| SCHEMBL8723905 | 0.85 | MTNR1A (0.46) | PRMT5MTNR1AMTNR1BDPP4GRIN2B | |
| SCHEMBL6262070 | 0.85 | EPHX2 (0.47) | PRMT5MTNR1AMTNR1BDPP4GRIN2B | |
| SCHEMBL7334700 | 0.85 | MTNR1A (0.47) | PRMT5MTNR1AMTNR1BDPP4GRIN2B | |
| Hydrochloric Acid SCHEMBL7334726 | 0.84 | MTNR1A (0.46) | PRMT5MTNR1AMTNR1BDPP4GRIN2B | |
| Hydrochloric Acid SCHEMBL10493763 | 0.84 | EPHX2 (0.46) | PRMT5MTNR1AMTNR1BDPP4GRIN2B | |
| SCHEMBL24651034 | 0.83 | GRIN2B (0.50) | PRMT5MTNR1AMTNR1BGRIN2BMEN1 | |
| SCHEMBL13981017 | 0.82 | MTNR1A (0.51) | PRMT5MTNR1AMTNR1BDPP4GRIN2B | |
| SCHEMBL26291183 | 0.82 | PRMT5 (0.47) | PRMT5MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |